Option a) false.
By handshaking lemma you can argue that degree of n must be odd but it doesn't mean it will be 1 always.
For example 1,4,4,4,4,3 is a valid degree sequence.
B) false.
Suppose the graph has 2 component as degree sequence G1 = 1,4,4,4,4,3 and G2= 4,4,4,4,4.
Which means it is not always true that graph is connected.
C) True
Vertex 1 and vertex n should be a vertex of same component of graph otherwise it will not follow handshaking lemma. Graph is undirected and vertex 1 and n are connected so, there must be a path from 1 to n.
D) false
Not every spanning tree will contain the edge joining 1 to n.