If we use the subset construction method to build the DFA and if the NFA has $n$ states, then the states in the DFA can be any subset of the $n$ states and we know that the total number of subsets of $Q$ is given by $P(Q)$ which is the powerset of Q.
To put it another way, if $n$ is the number of states of the DFA, it has $2^n$ subsets of states. Each subset corresponds to one of the possibilities that the DFA must remember, so the DFA must contain at most $2^n$ states.
I am not sure what minimisation of NFA means - it is not known to have any simple algorithm.