option 1 – 2 entities so are will be used as it is plural.
option 2 – contrast of option A so wrong
option 3 – families, s suffix i.e plural so we can't use is, so wrong
option 4 – family is a singular word, even it is a group of people the word is a singular so is will be used so option 4 is right.
So option 1 and 4