(A) $\mathrm{L1}=\mathrm{L1}+\mathrm{L2}$ This performs concatenation. It creates a new list by joining L1 and L 2 and then assigns this new list back to the variable L 1 . The result is $[1,2,3,4,5,6]$.
(B) $\mathrm{L1}.$extend$(\mathrm{L2})$: The .extend() method is a mutator. It takes an iterable (L2) and adds all its elements to the end of the original list (L1) in-place. The result is L1 = $[1,2,3,4,5,6]$.
(C) $\mathrm{L1}.$append$(\mathrm{L2})$: The .append() method adds its argument as a single element to the end of the list. The result would be $\mathrm{L1}=[1,2,3,[4,5,6]]$.
(D) $\mathrm{L1} = \mathrm{L2}.$extend$(\mathrm{L1})$: The .extend() method, being an in-place mutator, returns None. This statement would assign None to L1, making L1 $=$ None.